What is a key sign of copper toxicity?

A key sign of copper toxicity is Wilson's disease, which is a genetic disorder that leads to excessive accumulation of copper in the body, primarily affecting the liver and brain. In individuals with Wilson's disease, the body's ability to excrete copper is impaired, resulting in toxicity. This condition can cause a wide range of symptoms, including liver damage, neurological issues, and psychiatric disturbances.

Wilson’s disease is directly related to copper overload, making it a significant indicator of copper toxicity. The other options represent different medical conditions or symptoms that are not directly indicative of copper toxicity. For instance, anemia can be caused by a variety of factors and is not specifically related to copper levels, while hemochromatosis pertains to iron overload rather than copper. Fatigue is a common symptom associated with many health issues, making it too nonspecific to be a definitive sign of copper toxicity. Therefore, Wilson's disease stands out as the clear association with excessive copper accumulation.